ANUA PDRN 100 Hyaluronic Acid Booster Toner — Régénération Cellulaire

The Sodium DNA (100ppm) is the cosmetic form of PDRN — these salmon DNA fragments activate your cells' A2A receptors, triggering a biological cascade: collagen synthesis, cell proliferation, inflammation reduction. Unlike traditional humectants, it doesn’t just hydrate: it provides your skin with the nucleotides needed to repair itself from within.

TheHydrolyzed Hyaluronic Acid (0.5ppm) penetrates the epidermis thanks to its low molecular weight — it saturates the deeper layers with water, while the crosspolymer Hyaluronic Acid/Hydrolyzed Collagen (0.05ppm) forms a plumping film on the surface.

The Copper Tripeptide-1 protects against oxidative stress while stimulating cell renewal. TheAcetyl Glutamine strengthens the skin barrier and maintains water balance. The Panthenol (pro-vitamin B5) soothes immediately, while extracts of Curcuma Longa Root and Glycine Soja Seed even out the complexion.

☀️ Morning

1. After your cleanser, dispense 2-3 pumps into clean palms
2. Gently pat over the entire face and neck until fully absorbed
3. Let sit for 30 seconds before your serum or moisturizer
4. If you use the PDRN Hyaluronic Acid Capsule 100 Serum, apply it right after: clinical study shows +17.57% additional hydration compared to serum alone

🌙 Evening

1. Same routine after double cleansing
2. For a flash mask effect: soak reusable cotton pads and place them for 5-7 minutes on dry areas (cheeks, forehead)
3. Follow with your night actives (retinol, AHA) — PDRN strengthens the barrier, reducing potential irritation

Do you recognize your skin here?

• Systematic tightness after cleansing, need for an ultra-hydrating base before makeup
• Uneven texture, rough feel — gentle enzymatic exfoliation (sugarcane extract) smooths without stripping
• Dull, tired skin lacking bounce: PDRN stimulates endogenous collagen production
• Validated sensitive skin : irritation test completed, 100% of participants (n=51) found it gentle enough for daily use
• Post-dermatological treatment (peeling, laser): PDRN speeds up healing and soothes inflammation

Note: If you have a fish or shellfish allergy, consult your dermatologist before use. When in doubt, do a patch test on your forearm 24 hours prior.

From the first application: +95.73% immediate hydration, 7.63% improvement in texture according to the clinical study on 51 participants. Your skin is supple, comfortable, ready to receive your active ingredients.

After 4 days of use: 100% of participants notice a sebum/hydration balance and an improvement in softness. Depressive volume (dehydration fine lines) decreases by 19.04%.

After 3-4 weeks: the complexion becomes more even (turmeric + soy), the texture refines. The "plumped skin" effect is confirmed — this is the collagen synthesis stimulated by PDRN working deeply.

Long-term use: lasting strengthening of the skin barrier, better resistance to aggressions (pollution, stress), increased resilience to exfoliating anti-aging treatments.

What is the difference between this toner and the other ANUA toners (Heartleaf, Niacinamide, Azelaic Acid)?

The Heartleaf 77% targets immediate soothing (reactive skin, redness). The Niacinamide Tranexamic Acid Booster Toner works on pigmentation spots and radiance. The Azelaic Acid 3 CICA regulates sebum and clarifies imperfections. This PDRN 100 Booster Toner focuses on deep cellular regeneration and structural hydration — it is an "anti-aging" toner in the biological sense of the term.

How long does a 250ml bottle last?

Used morning and evening (about 3ml per day), a bottle lasts 2.5 to 3 months. If you use it only once a day or as a short course, it can last up to 5-6 months.

Can I use it with my ANUA PDRN serum?

Absolutely — it is even recommended by the brand. The official clinical study shows that the combination of PDRN toner + PDRN serum improves hydration by 72.70% compared to 55.13% with the serum alone. The toner opens aquaporin channels, facilitating serum penetration.

Does it feel sticky under makeup?

No. 100% of testers confirm a watery, non-sticky texture. It creates a dewy base that improves foundation adherence (the "skin flooding" effect). Just allow 1 minute for absorption before applying your BB cream.

Is it compatible with retinols/acids?

Yes. PDRN does not interfere with exfoliating or regenerating actives. It even strengthens skin tolerance by reinforcing the barrier — useful if your retinol usually makes your skin tight.

Is PDRN really effective topically, or does it need to be injected?

PDRN injections (like Rejuran) deliver a higher concentration directly into the dermis — so the effects are faster and more intense. But topical formulas like this use encapsulation systems and optimized molecular weights to penetrate the skin barrier. The benefits are real, documented by clinical studies, but gradual (4-6 weeks vs. 1-2 weeks for injectables).

ANUA, founded in South Korea, embodies this holistic philosophy that beauty of your skin depends not only on cosmetics but also on mental balance and lifestyle. The name "ANUA" plays on "A New A" — a new beginning for your skin, without artifice.

The brand favors pure ingredients, organic when possible, minimalist formulas (no unnecessary fragrances, no silicones). All products are 100% made in Korea, with eco-friendly packaging and strict certifications. The Heartleaf 77% Soothing Toner and the 5-Zero Mild Sun Cream have become international best-sellers thanks to their uncompromising effectiveness.

With the PDRN 100 range, ANUA takes a step forward: integrating a cutting-edge clinical active ingredient (salmon DNA, used in medical dermatology since the 1980s in Italy and Korea) into accessible daily skincare. It promises cellular regeneration at home, without injections.

Discover the entire ANUA range

Complete INCI:

Water, Butylene Glycol, Glycerin, Pentylene Glycol, Propanediol, Saccharum Officinarum (Sugarcane) Extract, Xylitylglucoside, Glycine Soja (Soybean) Seed Extract, Malachite Extract, Xylitol, Melia Azadirachta Leaf Extract, Vincetoxicum Atratum Extract, Melia Azadirachta Flower Extract, Coccinia Indica Fruit Extract, Althaea Rosea Flower Extract, Aloe Barbadensis Flower Extract, Hydrolyzed Hyaluronic Acid (0.5ppm), Solanum Melongena (Eggplant) Fruit Extract, Ocimum Sanctum Leaf Extract, Corallina Officinalis Extract, Curcuma Longa (Turmeric) Root Extract, 1,2-Hexanediol, Betaine, Hydroxyacetophenone, Panthenol, Ethylhexylglycerin, Anhydroxylitol, Allantoin, Sodium DNA (100ppm), Dipropylene Glycol, Octanediol, Phosphatidylcholine, Tocopherol, Hyaluronic Acid/Hydrolyzed Collagen Crosspolymer (0.05ppm), C12-13 Alketh-9, Dipotassium Phosphate, Acetyl Glutamine, Copper Tripeptide-1, Cellulose Gum, Disodium EDTA, Xanthan Gum.

The heavyweights: Sodium DNA (PDRN) at the top of the active list, triple hyaluronic acid (low, medium, high molecular weight), copper peptide, modified amino acids. Fragrance-free, essential oil-free, silicone-free formula — designed not to interfere with your other actives.

Aquaxyl hydrating system: Xylitylglucoside + Anhydroxylitol + Xylitol form a patented complex that optimizes the skin’s water flow — increasing endogenous NMFs (natural moisturizing factors), strengthening cellular cohesion.