BIO HEAL BOH Panthecell Repair Cica Cream Mist — Brume Clinique Biphasée

This restorative mist combines two distinct layers — cream + essence — for a double impact effect on the weakened skin barrier.

Centella Asiatica Extract (10%): this is not just a soothing extract. The concentration here includes centellosides (asiaticoside, madecassoside, asiatic acid, madecassic acid), these pentacyclic triterpenes that stimulate hyaluronic acid synthesis and accelerate healing. Recognized in dermatological protocols for eczema and microlesions.

Panthenol (1%): provitamin B5 in its most bioavailable form. A powerful humectant, it attracts water into the epidermis while boosting the production of barrier lipids. Studies show its anti-inflammatory effectiveness and its role in fibroblast proliferation, the cells that produce collagen.

12 bioactive peptides : this set includes Acetyl Hexapeptide-8 (nicknamed "Botox-like"), Acetyl Octapeptide-3, Copper Tripeptide-1, and 9 other amino acid chains. Their mission: to smooth, firm, stimulate collagen synthesis, and strengthen skin immunity. A rare clinical arsenal in a mist.

CGF (Centella Growth Factor) : proprietary complex combining Centella Asiatica Leaf Extract, glycerin, and citric acid. It encapsulates healing actives for prolonged release.

Bio Oliosome Tech : encapsulation technology that miniaturizes actives into lipid microparticles. Goal: to penetrate the stratum corneum and deliver ingredients deep where repair begins.

☀️ Morning routine

1. After your toner or essence, shake the bottle vigorously to mix the two phases (cream + water).
2. Spray 15-20 cm from your face, eyes closed, sweeping from top to bottom.
3. Gently pat with your palms to help absorption — the texture remains light, never sticky.
4. Follow with your usual moisturizer if your skin is very dry, or go straight to sunscreen.

🌙 Evening routine

1. Same protocol after toner: shake, spray, pat.
2. If you use strong actives (retinol, acids), apply the mist right after to soothe inflammation and strengthen the barrier.
3. It can also serve as a “buffer”: spray it 5 minutes before your retinol to reduce irritation without diluting its effectiveness.

💡 Layering tip : this two-phase mist also works during the day, even over makeup. A quick hydration boost when your skin feels tight.

This clinical mist has been tested non-comedogenic and designed for distressed skin barriers:

• Reactive sensitive skin : diffuse redness, burning sensation upon contact with water, intolerance to cosmetics. The 10% Centella + Panthenol form a documented anti-inflammatory duo.
• Altered barriers post-treatment : after peeling, dermabrasion, laser, or even a prolonged period under retinol. The mist accelerates tissue regeneration.
• Dehydrated skin with oily tendency : it controls reactive seborrhea (when the skin produces sebum to compensate for dehydration) while hydrating without occlusion. Interest test for combination/oily skin confirmed.
• Skin with microlesions or recent scars : asiaticoside stimulates the synthesis of type I and III collagen, promoting clean healing.
• Skin seeking simplification : this mist replaces both a light moisturizer and a soothing lotion. Time-saving guaranteed.

To avoid if : you have very dry/desert-like skin without any other moisturizing product — this mist alone will not be enough, it must be complemented by an occlusive cream.

From the first application : immediate soothing effect. Diffuse redness fades, the sensation of heat decreases. The two-phase texture leaves a "cushion" finish, neither greasy nor dry.

After 1 week : the skin better tolerates irritating active ingredients. Post-cleansing tightness disappears. The barrier begins to rebuild, measurable by reduced transepidermal water loss (TEWL).

After 2 weeks : skin texture refines. Internal clinical studies by BIO HEAL BOH show an improvement in skin thickness and density within this time frame. Visually, the complexion appears less dull, more plump.

After 4-6 weeks : increased resilience against aggressors (pollution, temperature changes, stress). Recent scars heal faster. Vertical pores (a sign of loss of elasticity) tighten thanks to peptides.

What this mist DOES NOT do : it does not treat active cystic acne, does not replace a concentrated anti-pigmentation serum, and does not compete with retinol for smoothing established wrinkles. It repairs, it does not transform .

Why do you need to shake the bottle before each use?

The two phases (cream + essence) naturally separate when at rest. Shaking creates a temporary emulsion that allows you to spray both lipophilic actives (peptides, ceramides) and hydrophilic ones (Centella, Panthenol) at the same time. Without shaking, you only get an aqueous layer.

Can it be used with acids (AHA, BHA) or retinol?

Absolutely. It is even recommended. Panthenol at 1% has been shown to reduce irritation caused by preservatives, UV filters, and exfoliating actives. Apply your mist right after your acid or retinol to soothe inflammation without compromising their effectiveness.

Is it really non-comedogenic despite the cream layer?

Yes, it has passed the official non-comedogenic test. The Bio Oliosome technology miniaturizes lipids into microcapsules that penetrate without clogging pores. Many users with combination/oily skin report better shine control precisely because it rebalances the barrier.

How long does a 120 ml bottle last with daily use?

About 2 to 3 months if you use it morning and evening. One to two sprays are enough to cover the face — it’s a mist, not a liquid toner to pour. If you also use it for daytime touch-ups, expect about 6 to 8 weeks.

What is the difference with the Panthecell Repair Cica Cream from the same range?

The mist is lighter, biphasic, and designed for quick absorption plus versatile use (layering, touch-ups, anti-irritation buffer). The cream is a rich, occlusive texture meant to seal in hydration as the last step. If your skin is dry, you can combine both: mist mid-routine, cream to finish.

Is it suitable for acne-prone skin under dermatological treatment?

Yes. Dermatological protocols (isotretinoin, tretinoin, benzoyl peroxide) weaken the barrier. This mist, tested on sensitive skin and non-comedogenic, helps manage side effects (dryness, peeling, redness) without interfering with treatments. Always ask your dermatologist if in doubt.

BIO HEAL BOH (formerly Botanic Heal boH) was launched in 2013 as the first private label brand of Olive Young, the South Korean beauty giant that now has over 1,370 stores. Originally focused on botanicals, the brand shifted towards "bio-dermatology" — a blend of cellular biology and clinical dermatology — to meet the demand of Korean consumers seeking proven effectiveness, not empty marketing.

What sets BIO HEAL BOH apart is its own research laboratory, the BIO SKIN LAB, where teams study the skin microbiome, bioactive peptides, and encapsulation technologies. Formulas are clinically tested before launch, and results — skin thickness, density, TEWL — are published. No "revolutionary" claims without proof.

The Panthecell™ range, which includes this mist, is based on the concept of "targeted repair": restoring the barrier function before treating visible signs of aging. This is what Koreans call "slow-aging," a preventive rather than corrective approach. In 2024, the brand’s Probioderm 3D Lifting Cream was the number one anti-aging cream in Korea — a status earned through rigor, not buzz.

Today, BIO HEAL BOH exports to over 20 countries and remains 100% made in South Korea, with some of the strictest quality control standards in the industry. A brand that doesn’t play the flashy luxury card, but focuses on accessible, documented performance.

Discover the full BIO HEAL BOH range

Full INCI : Water, Glycerin, Centella Asiatica Extract (10%), Triethylhexanoin, Hydrogenated Poly(C6-14 Olefin), Butylene Glycol, Pentylene Glycol, Methylpropanediol, Panthenol (1%), Beta-Sitosterol, Centella Asiatica Leaf Extract, Acetyl Hexapeptide-8, Ascorbic Acid Polypeptide, Acetyl Octapeptide-3, Acetyl Tetrapeptide-2, Acetyl Tetrapeptide-3, Acetyl Tetrapeptide-5, Acetyl Tetrapeptide-9, Copper Tripeptide-1, Nonapeptide-1, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Streptococcus Thermophilus Ferment, Tocopherol (Vitamin E), Chondrus Crispus Extract, Saccharum Officinarum (Sugarcane) Extract, Apple Juice, Candida Bombicola/Glucose/Methyl Rapeseedate Ferment, Helianthus Annuus (Sunflower) Seed Oil, 1,2-Hexanediol, Betaine, Trilaureth-4 Phosphate, Ethylhexylglycerin, Polyquaternium-51, Sodium Phytate, Citric Acid, Lecithin, Escin, Dipropylene Glycol, Carnosine.

Star Breakdown : The 10% Centella extract is combined with Centella Asiatica Leaf Extract to maximize active centellosides. The 1% Panthenol is dosed above the cosmetic threshold (usually 0.5%), ensuring a clinically measurable repairing effect. The 12 peptides (Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Copper Tripeptide-1, etc.) form a rare anti-aging and healing cocktail in a mist. Vitamin E (Tocopherol) protects membrane lipids from oxidation. Streptococcus Thermophilus Ferment is a fermented probiotic that supports the skin microbiome.

Free From : denatured alcohol, sulfates, parabens, silicones, synthetic fragrances. Formulated to minimize allergy risks — skin irritation test completed for sensitive skin.

Note : The INCI list comes from official databases (INCIDecoder, Skinsort) and authorized resellers. If you need to check a specific ingredient for a known allergy, always refer to the label on the product received.